Lafutidine Good Manufacturer supply High Quality 118288-08-7
- Molecular Formula:C22H29N3O4S
- Molecular Weight:431.556
- Appearance/Colour:Yellowish white crystalline powder
- Vapor Pressure:1.12E-19mmHg at 25°C
- Melting Point:92.7-94.9°
- Refractive Index:1.598
- Boiling Point:704.2 °C at 760 mmHg
- PKA:13.13±0.46(Predicted)
- Flash Point:379.7 °C
- PSA：103.88000
- Density:1.252 g/cm3
- LogP:3.85510
Lafutidine (118288-08-7) Usage
Lafutidine is a histamine H2 receptor antagonist with gastroprotective activity. It inhibits histamine-induced cAMP production in CHO cells expressing human histamine H2 receptors when used at a concentration of 10 nM. Intragastric administration of lafutidine (3, 10, and 30 mg/kg) reduces hemorrhagic esophageal lesion size and gastric acid secretion in a rat model of pyloric ligation-induced reflux esophagitis. It prevents 5-fluorouracil-induced intestinal mucositis, diarrhea, and body weight loss in wild-type, but not Trpv1-/- or sensory deafferented, mice when administered at doses ranging from 3 to 30 mg/kg. Lafutidine (10 mg/kg) also reduces indomethacin-induced antral ulcer size in wild-type, but not chemically-deafferented, rats.
How to get the best price on Lafutidine?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Lafutidine . You can buy high quality, low price Lafutidine 118288-08-7 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
