Valacyclovir hydrochloride Good Manufacturer supply High Quality 124832-27-5
- Molecular Formula:C13H21ClN6O4
- Molecular Weight:360.801
- Appearance/Colour:White to off-white crystalline power
- Vapor Pressure:7.95E-14mmHg at 25°C
- Melting Point:170-172 °C
- Refractive Index:1.673
- Boiling Point:588.4 °C at 760 mmHg
- Flash Point:309.7 °C
- PSA：151.14000
- Density:1.55g/cm3
- LogP:1.28590
Valacyclovir hydrochloride (124832-27-5) Usage
Valacyclovir hydrochloride, an orally active L-valyl ester of the potent antiviral agent aciclovir, was launched in 1995 in the United Kingdom for the treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes, including initial and recurrent genital herpes. As a prodrug, valaciclovir has an improved pharmacokinetic profile to aciclovir. It is rapidly absorbed after oral administration and extensively converted to aciclovir via first-pass metabolism to achieve plasma levels of aciclovir comparable to those seen with aciclovir via i.v. route. Valacyclovir is then activated selectively in virus-infected cells by viral thymidine kinase to form aciclovir triphosphate in a stepwise fashion. This active species inhibits viral DNA polymerase via irreversible binding to the active site of the enzyme. Once aciclovir is incorporated into the elongating viral DNA, it terminates replication of the viral DNA strand, an antiviral mechanism unique to aciclovir. Valacyclovir is reportedly in clinical trials for the suppression of cytomegalovirus infection and disease in renal transplant patients.
How to get the best price on Valacyclovir hydrochloride?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Valacyclovir hydrochloride . You can buy high quality, low price Valacyclovir hydrochloride 124832-27-5 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
