166663-25-8/Anidulafungin

Quick Details
Molecular Formula:C58H73N7O17
Molecular Weight:1140.25
CasNo:166663-25-8

  • Product Details

    Anidulafungin Good Manufacturer supply High Quality 166663-25-8

    • Molecular Formula:C58H73N7O17
    • Molecular Weight:1140.25
    • Vapor Pressure:0mmHg at 25°C 
    • Refractive Index:1.688 
    • Boiling Point:1477 °C at 760 mmHg 
    • PKA:9.86±0.26(Predicted) 
    • Flash Point:847 °C 
    • PSA:377.42000 
    • Density:1.47 g/cm3 
    • LogP:0.65480 

    Anidulafungin (166663-25-8) Usage

    Anidulafungin, a semi-synthetic derivative of echinocandin B, has been developed and launched as an intravenous treatment for serious fungal infections, such as candidemia, Candida-derived peritonitis, intra-abdominal abscesses, and esophageal candidiasis. As a non-competitive inhibitor of 1,3-b-D-glucan synthase, which is responsible for the formation of glucan polymers, anidulafungin interferes with the cell wall synthesis of most pathogenic fungi. This mode of action is characteristic of the echinocandin class of antifungals. While the first member of this class, cilofungin, was withdrawn due to toxicity associated with the formulation vehicle, anidulafungin follows the successful introduction of caspofungin and micafungin. Compared to the other echinocandins, anidulafungin appears to be more potent (MIC90 ofr0.25 mg/mL for C.albicans, 0.5 mg/mL for C.glabrata, 1 mg/mL for C. krusel and C.tropicalis, 2mg/mL for C.lusitaniae, and 2 mg/mL for Aspergillus spp) and is devoid of significant drug interactions since it is neither an inhibitor nor substrate of the cytochrome P450 isoenzymes. The emergence of the echinocandins circumvents the concern regarding the rising resistance to the azole and amphotericin B antifungals; no cross-resistance is expected because the echinocandins work at the cell wall rather than the cell membrane.

    How to get the best price on Anidulafungin?

    Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Anidulafungin . You can buy high quality, low price Anidulafungin 166663-25-8 here.

    Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.

    Milestones

    • 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
    • 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
    • 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
    • 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
    • 2023yearBusiness continues to expand, Production and Sales teams continue to grow
    • 2026yearPlans to set up foreign branches


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