Valsartan Good Manufacturer supply High Quality 137862-53-4
- Molecular Formula:C24H29N5O3
- Molecular Weight:435.526
- Appearance/Colour:white crystalline powder
- Vapor Pressure:1.06E-19mmHg at 25°C
- Melting Point:116-117 °C
- Refractive Index:1.586
- Boiling Point:684.9 °C at 760 mmHg
- PKA:3.56±0.10(Predicted)
- Flash Point:368 °C
- PSA：112.07000
- Density:1.212 g/cm3
- LogP:4.16170
Valsartan (137862-53-4) Usage
Diovan(Valsartan) was launched in Germany and the UK as an angiotensin Ⅱ antagonist for use as an antihypertensive agent. Biphenylbromomethyl nitrite serves as the starting material for a three step synthesis of the compound, in which the (S)- enantiomer is more active than the (R)-enantiomer. Valsartan is a nonpeptide drug which is a highly specific antagonist of the AT1 receptor and is potent and orally active. This receptor is responsible for angiotensin Ⅱ cardiovascular effects (aldosterone and catecholamine secretion, vascular constriction, positive inotropic response and renal effects). Unlike losartan, it is not a prodrug and a single daily dose is comparible in activity to the ACE drug enalapril. It also did not exhibit the coughing side effect observed with ACE inhibitors. Diovan(Valsartan) is slowly metabolized (long lasting) with its main metabolite being significantly less active. There was no evidence of rebound hypertension when drug treatment was terminated and was as effective as the dihydropyridine Ca antagonist anlodipine.
How to get the best price on Valsartan?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Valsartan . You can buy high quality, low price Valsartan 137862-53-4 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
![4,7-DIAZA-SPIRO[2.5]OCTANE DIHYDROCHLORIDE](/upload/2024/6/fc63e489-89ad-4f1d-bdc9-e1b5b4bc4fbf.png)
