Mebendazole Good Manufacturer supply High Quality 31431-39-7
- Molecular Formula:C16H13N3O3
- Molecular Weight:295.298
- Appearance/Colour:white to yellowish powder
- Melting Point:288.5 °C
- Refractive Index:1.702
- Boiling Point:436.98°C (rough estimate)
- PKA:pKa 3.43/9.93(H2O,t =25,I=0.025) (Uncertain)
- PSA：84.08000
- Density:1.388 g/cm3
- LogP:3.04520
Mebendazole (31431-39-7) Usage
Mebendazole is a broad-spectrum anthelmintic that is active against both larval and adult stages of nematodes selectively binding the β-subunit of tubulin, thereby inhibiting intestinal microtubule synthesis in the parasite (IC50 = 0.19 μM for Giardia in vitro). As a tubulin-binding agent, mebendazole also possesses antitumor properties, inducing apoptosis of various human carcinomas both in vitro and in vivo, thus preventing their growth and migration. Furthermore, mebendazole has been used to inhibit hedgehog signaling in cancer cells via suppression of the formation of the primary cilium, a microtubule-based organelle that functions as a signaling hub for hedgehog pathway activation. Additionally, mebendazole has been shown to stabilize the transcriptional activator HIF-1α and its downstream targets, abrogating oxidative neuronal death in primary neurons.
How to get the best price on Mebendazole?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Mebendazole . You can buy high quality, low price Mebendazole 31431-39-7 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
